2015 Clinical Trial: Thunder God Vine VS Acitretin in Psoriasis

2015 Clinical Trial: Thunder God Vine VS Acitretin in Psoriasis
October 16, 2017 Nathalie

A Psoriasis natural treatment

Medicinal Thunder God Vine is a common Psoriasis natural treatment in China for the past 30 years.

It is also a first intention prescription for a number of other autoimmune conditions. It is considered as a natural DMARD that is both safe and usually more efficient than the 5 common DMARDs. Although medicinal Thunder God Vine is not known outside of China, recent clinical studies have been carried out and published in English.

To illustrate the efficacy of Thunder God Vine in Psoriasis, this study is quite interesting, as it features the improvement of Psoriasis over a very short period of time.

Thunder God Vine = TwHF = Tripterygium wilfordii Hook F = Lei Gong Teng

Here I quote the introduction of the study:

“Extracts of the Chinese herb Tripterygium wilfordii Hook F (TwHF), also known as “Lei Gong Teng,” are used as one of the most common systemic treatments for inflammatory and immune disorders including psoriasis, rheumatoid arthritis (RA), Crohn’s disease, nephritis, and systemic lupus erythematosus.”

Basically, this means that in China, medicinal Thunder God Vine is a very common treatment in a number of autoimmune conditions.

The study

The study included 115 patients with moderate to severe Psoriasis Vulgaris (affecting at least 10% of the body surface).

  • 58 patients took Thunder God Vine extract of the T2 type. In other words, the T2 is the methanol-chloroform medicinal extract. That is to say the same type as the many commercial presentations seen through this website. The dosage is of 1 to 1,5 mg/kg/day. Patients took 3 X 20mg = 60mg / day. This is the equivalent of the lower dosage basis for a 60kg patient.
  • 57 patients took Acitretin at the dose of 30mg/day. Usually, the maintenance dose is of 25 to 50 mg orally once a day.

The goal was to compare the efficacy and safety of this Psoriasis natural treatment to that of Acitretin over a period of 8 weeks.

The Results

Psoriasis Natural Treatment: severe Psoriasis treated with Thunder God Vine

In case you would like the complete document, it is available from the US National Library of Medicine / National Institutes of Health website (publisher): Efficacy and Safety of Tripterygium wilfordii Hook F Versus Acitretin in Moderate to Severe Psoriasis Vulgaris: A Randomized Clinical Trial.

Here I quote the conclusion of the study:

“There was no significant difference in treatment efficacy between the TwHF (Thunder God Vine) and Acitretin groups within 8 weeks, but there were fewer treatment-related adverse events in the TwHF (Thunder God Vine) group.”


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